1 The subsequent adverse reactions transpired in at the very least 5% of Depakote-treated patients and at an equal or larger incidence for placebo than for Depakote: flu syndrome and pharyngitis.severe multiorgan reactions. Treatment with DEPAKOTE may possibly lead to critical multiorgan reactions which can be everyday living-threatening or might c… Read More

A lot less than three% of an administered dose is excreted unchanged in urine. The relationship between dose and full valproate focus is nonlinear; concentration isn't going to improve proportionally Together with the dose, but somewhat, improves to your lesser extent as a consequence of saturable plasma protein binding. The kinetics of unbound dru… Read More